Sahay Lab is engineering lipid-based nanoparticles for delivery of mRNA based therapeutics
Chemistry of Lipid Nanoparticles for RNA Delivery | Accounts of Chemical Research
Chemistry of Lipid Nanoparticles for RNA Delivery
ConspectusLipid nanoparticles (LNPs) are a type of lipid vesicles that possess a homogeneous lipid core. These vesicles are widely used in small-molec...
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New content online: Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation http://dlvr.it/SCmFdl
New content online: Nanomedicine hitchhikes on neutrophils to the inflamed lung http://dlvr.it/SCmhj0
Pleased to share our new @naturenano paper, developing nanoparticles with tropism to neutrophils, investigating supramolecular sensing, & fighting ARDS & sepsis. Thanks to collaborators @SMitragotri @LahannLab @RotelloGroup @PennMedicine #nanomedicine
Supramolecular arrangement of protein in...
Nature Nanotechnology - Neutrophils are the first responders in acute inflammatory events such as acute respiratory distress syndrome and tend to home...
@sahayg1 @NatureNano @SMitragotri @LahannLab @RotelloGroup @PennMedicine Thanks @sahayg1 for the great News & Views article associated with this paper. We need to collaborate sometime soon! Your elegant tools for understanding & controlling mRNA-LNPs' endosomal escape might synergize well with our neutrophil targeting!
Nanomedicine hitchhikes on neutrophils to the...
Nature Nanotechnology - Supramolecular arrangement of proteins provides nanoparticles with neutrophil tropism via complement opsonization during an ac...