Sahay Lab
We are developing novel lipid based nanoparticles to deliver mRNA based therapies for the treatment of cystic fibrosis, retinal degeneration and against SARS-CoV2.
Located in the OSU/OHSU College of Pharmacy
We are located at the Robertson Life Science Building on the OHSU campus at the Southwest waterfront in Portland, Oregon.
Located in the OSU/OHSU College of Pharmacy
We are located at the Robertson Life Science Building on the OHSU campus at the Southwest waterfront in Portland, Oregon.
Our Goal
The long-term goal of our laboratory is to develop efficient non-viral vectors for intracellular delivery of nucleic acids.
Our focus is on three main research areas:
- to understand cellular trafficking of nanoparticles in-vivo and develop approaches to overcome endosomal barriers;
- to develop messenger (mRNA)-based gene therapy for the treatment of cystic fibrosis and eye disorders;
- to exploit supramolecular assembly of peptide-based nanomaterials for cell type specific delivery.